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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
Anyone else tried everything for their depression/ptsd? I've pretty much done it all. 4 years of therapy including emdr. All the meds, ketamine infusions, ECT(gave me a bunch of permanent memory loss) neurofeedback, craniosacral therapy, tms, and recently just did psilocybin assisted therapy and ya it just made it worse. Some of us are truly treatment resistant. At least when I finally get the guts to ctb I can be proud that I tried everything to get better..thanks for coming to my Ted Talk <3
 
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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
What makes you depressed?
I have a brain injury and have always had clinical depression since I was a kid and just dont find enjoyment in stuff. You ?
 
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HeyBoogahJr

HeyBoogahJr

I'm still here.
Apr 25, 2026
135
I'm sorry to hear that, I can see why you want to ctb. No pressure or anything, but why don't you have the guts?

I've been lonely for a long while and I'd like to move on.
 
divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
I'm sorry to hear that, I can see why you want to ctb. No pressure or anything, but why don't you have the guts?

I've been lonely for a long while and I'd like to move on.
Im afraid of failing and getting another brain injury. I understand <3
 
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HeyBoogahJr

HeyBoogahJr

I'm still here.
Apr 25, 2026
135
Im afraid of failing and getting another brain injury. I understand <3
Yeah I get that, its terrifying of having to deal with more when you just want to go. Have you found enjoyment in nothing since you were a kid? If you don't mind me asking?
 
divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
Yeah I get that, its terrifying of having to deal with more when you just want to go. Have you found enjoyment in nothing since you were a kid? If you don't mind me asking?
Besides in animals not really
You ?
 
HeyBoogahJr

HeyBoogahJr

I'm still here.
Apr 25, 2026
135
What do you like about animals? (Please don't let it be torture)

I enjoy general life moments with other people, game I like, anime I watch, but being lonely can be hard and I have no reason that is worth sticking around. Being alive is boring ya' know?
 
divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
What do you like about animals? (Please don't let it be torture)

I enjoy general life moments with other people, game I like, anime I watch, but being lonely can be hard and I have no reason that is worth sticking around. Being alive is boring ya' know?
No not at all! Their innocence and ability to just live in the moment . My dogs unconditional love he gives. Being alive is so boring. I spend so much time doom scrolling
 
HeyBoogahJr

HeyBoogahJr

I'm still here.
Apr 25, 2026
135
Glad to hear it, animals are adorable fr fr. Dogs sure are nice, I've thought about seeing a dog at some dog shelter but mum wouldn't allow it, I also feel weird about the morals of having pets.

I read a book about Finding hope in depression, it was a really nice book (even if I don't care to take it seriously anymore) I could share some ideas if you still want to try some stuff before the end?
 
http-410

http-410

nowhere
Sep 12, 2020
1,122
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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
Glad to hear it, animals are adorable fr fr. Dogs sure are nice, I've thought about seeing a dog at some dog shelter but mum wouldn't allow it, I also feel weird about the morals of having pets.

I read a book about Finding hope in depression, it was a really nice book (even if I don't care to take it seriously anymore) I could share some ideas if you still want to try some stuff before the end?
Of course, than you <3
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Mdma isnt legal here , Ive heard good things about it for ptsd. They dont say much just to keep going to therapy. Ya ketamine was dissapointing huh
 
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Pluto

Pluto

Cat Extremist
Dec 27, 2020
6,917
therapy-cat-after-told-them-my-problems-imgflipcom-did-not-sign-up-dis-hooman
 
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HeyBoogahJr

HeyBoogahJr

I'm still here.
Apr 25, 2026
135
Of course, than you <3

Mdma isnt legal here , Ive heard good things about it for ptsd. They dont say much just to keep going to therapy. Ya ketamine was dissapointing huh
The book is called Lost Connections by Johann Hari. It was a really refreshing read, I recommend it a ton fr. (No I'm not secretly Johann Hari.)

The main point was that depression is just a sign that you're disconnected from things you actually need. Here is what it mentioned:
  • Work with actual freedom: Doing stuff where you have zero control or say just wears you down. You need to feel like you matter.
  • Real connections: Loneliness is brutal fr. We need people we can be 100% real with without getting judged.
  • Intrinsic values: Chasing money or status is a trap. True happiness comes from internal stuff like growth and helping people.
  • Nature: Getting outside around trees or animals resets your system. We aren't meant to be trapped inside staring at screens.
  • Community: Volunteering or joining a group gives you a reason to get out and connects you to something bigger.
  • Releasing trauma: Pushing down old hurts just traps them in your body. You gotta talk about it with someone you trust to let it go.
I hope one of these help out.

I'm always down to talk about anime, games, or literally whatever. No pressure, but I'm here.

I was in a depressive funk so I joined a gardening group and it was pretty nice for a while, but I got banished so ya' know back to dying.
 
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L

LittleJem

Visionary
Jul 3, 2019
2,850
yes, nearly everything, rTMS also. It's pricey. Scalp acupuncture. No dice. Meds. Yup
 
E

Endisclose

Arcanist
Oct 23, 2023
409
Anyone else tried everything for their depression/ptsd? I've pretty much done it all. 4 years of therapy including emdr. All the meds, ketamine infusions, ECT(gave me a bunch of permanent memory loss) neurofeedback, craniosacral therapy, tms, and recently just did psilocybin assisted therapy and ya it just made it worse. Some of us are truly treatment resistant. At least when I finally get the guts to ctb I can be proud that I tried everything to get better..thanks for coming to my Ted Talk <3
I've been wanting to say that I really like your username for a really long time..

I kinda feel the same way without trying any medication or therapy if that makes sense..I tried some supplements though, but they didn't help much.

I am just at a point where I feel like I've thrown the kitchen sink at it, but life has just upended everything. I've come to the realisation that what I have is an intractable condition - bipolar disorder+BPD+PTSD+OCD and that no amount of medication or therapy is going to change that fundamentally..
 
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A

aceHardlight

Not even sad, just dead inside
May 1, 2026
26
Have you tried Paroxetine? It is the strongest of all SSRI. Out of 5 SSRI/SNRI it was the only one that actually made a difference.

Then you could even try some stronger oldschool medications, like tricyclic antidepressants.

If you find a good doctor he may agree to try Nardil, which is a MAO inhibitor. This is the nuclear option, but it shows really promising results for treatment resistant depression, especially when anhedonia is involved.
 
dust-in-the-wind

dust-in-the-wind

Animal Lover
Aug 24, 2024
963
You and me are one in the same. I live right now for my dog. I have not tried psilocybin yet. You actually confirmed my fear of it making me worse. Have you tried any stimulant meds? My psych did prescribe them to me as they are used off label for TRD. They help somewhat. Can I ask what your brain injury is and did it cause your depression? I am at a loss as to why I am like this. No mental illness in my family.
 
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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
Have you tried Paroxetine? It is the strongest of all SSRI. Out of 5 SSRI/SNRI it was the only one that actually made a difference.

Then you could even try some stronger oldschool medications, like tricyclic antidepressants.

If you find a good doctor he may agree to try Nardil, which is a MAO inhibitor. This is the nuclear option, but it shows really promising results for treatment resistant depression, especially when anhedonia is involved.
Yes it helped for a bit then stopped. Nardil you have to be strict with diet Im not good with that
You and me are one in the same. I live right now for my dog. I have not tried psilocybin yet. You actually confirmed my fear of it making me worse. Have you tried any stimulant meds? My psych did prescribe them to me as they are used off label for TRD. They help somewhat. Can I ask what your brain injury is and did it cause your depression? I am at a loss as to why I am like this. No mental illness in my family.
I havent . I assumed they would make my anxiety worse. Psilocybin helps some people a lot though. It was a high dose and freaked me out so maybe at a lower dose it would have been effective
 
W

wine is fine but

whiskey's quicker
Jul 26, 2025
375
At least when I finally get the guts to ctb I can be proud that I tried everything to get better..thanks for coming to my Ted Talk <3
all anyone can ever ask of someone is that they try
i hope you can somehow find a way to enjoy yourself and be happy to continue

i have been lucky, in that pristiq was the first anti-depressant that i tried and it works well for me

i hope that somehow, something gets invented in the near future to help you to enjoy your life
 
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KuriGohan&Kamehameha

KuriGohan&Kamehameha

想死不能 - 想活不能
Nov 23, 2020
1,883
Girl, we are in a nearly identical situation, so I completely understand your frustration with all the unconventional and conventional options alike just... completely failing. Are you autistic as well? I've began to suspect for quite some time now that plays a major role in why so much is simply ineffective for me, not to mention autistic women are rarely included in any sorts of trials or research studies, so it is difficult to actually gather any data about this issue.

I've had PTSD since I was 5 years old, and later developed other issues as well, but absolutely nothing has helped. Like you, I've been through pretty much every medication and therapy out there. I've tried supplements, reading popular books, and also psychedelics at home despite them not being easily accessible in the places I've lived. The only thing that ever helped me was MDMA for a single day, and the side effects were quite extreme.

I feel really alone with this also, because people parrot over and over again that PTSD is completely curable or at the very least manageable with conventional exposure therapies, but this has not been my experience in the slightest. Not to mention, the way other people treat victims of SA is just completely disgusting and enough to make you feel small and disillusioned.
 
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Roadrunner

Roadrunner

Specialist
Mar 18, 2024
377
I think I read that the mother in the country duo the judds was therapy resistant, I could be wrong. I know this doesn't help but, I always enjoy reading your posts and replies to others. Same for dust in the wind. It'll be a sadder day for me when/if you choose to catch a bus, however with everyone that does, I always feel relief that their pain has finally ended. Doubt I'll ever find the testicular fortitude to go, I have so many regrets I've really become afraid to make any major life decisions. Good luck with whatever you choose, I wish you the best.
 
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T

truce9

New Member
Apr 30, 2026
2
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divinemistress87

divinemistress87

Angelic
Jan 1, 2024
4,938
Girl, we are in a nearly identical situation, so I completely understand your frustration with all the unconventional and conventional options alike just... completely failing. Are you autistic as well? I've began to suspect for quite some time now that plays a major role in why so much is simply ineffective for me, not to mention autistic women are rarely included in any sorts of trials or research studies, so it is difficult to actually gather any data about this issue.

I've had PTSD since I was 5 years old, and later developed other issues as well, but absolutely nothing has helped. Like you, I've been through pretty much every medication and therapy out there. I've tried supplements, reading popular books, and also psychedelics at home despite them not being easily accessible in the places I've lived. The only thing that ever helped me was MDMA for a single day, and the side effects were quite extreme.

I feel really alone with this also, because people parrot over and over again that PTSD is completely curable or at the very least manageable with conventional exposure therapies, but this has not been my experience in the slightest. Not to mention, the way other people treat victims of SA is just completely disgusting and enough to make you feel small and disillusioned.
Not autistic but I do have a tbi so I can relate with some things like the sensory overload issues and not understanding human behavior. Oh hearing about how treatable ptsd and depression is and never having any luck with relief from is so dissappointing huh :(. I havent been through SA but I have been through basically a physical assault so I can kind of relate. The trauma from it never ends
I heard recently about something called Ibogaine if you're interested. Sounds like it has potential, but then again I thought psilocybin did too.

Psilocybin has been helping people. I had a bad trip on it, I think those that have a positive experience with it benefit from it. I've looked into Ibogaine and 5 meo dmt if I can get to Mexico next year. Thank you <3
 
O

onedayillbok

Member
Apr 19, 2026
30
I relate so much. To this trying everything and never getting better. ECT with added ketamine at least numbed the urges for a while. Trying a new meds it's supposed to help, so far all that's happened is my urges and ideation have gotten worse.

My sn got seized by customers and I'm waiting for t eh second attempt for it.

From childhood sa, adult sa, child losses, and all the other life in between, I just can't find joy. Anywhere.
 
dust-in-the-wind

dust-in-the-wind

Animal Lover
Aug 24, 2024
963
I think I read that the mother in the country duo the judds was therapy resistant, I could be wrong. I know this doesn't help but, I always enjoy reading your posts and replies to others. Same for dust in the wind. It'll be a sadder day for me when/if you choose to catch a bus, however with everyone that does, I always feel relief that their pain has finally ended. Doubt I'll ever find the testicular fortitude to go, I have so many regrets I've really become afraid to make any major life decisions. Good luck with whatever you choose, I wish you the best.
Yes Naomi Judd killed herself via shotgun to the head a few years ago. She was 76 years old and she had treatment resistant depression. What's even sadder is she wrote a book a few years prior to her suicide about how she emerged from her depression and gave people hope to overcome it.
I think I read that the mother in the country duo the judds was therapy resistant, I could be wrong. I know this doesn't help but, I always enjoy reading your posts and replies to others. Same for dust in the wind. It'll be a sadder day for me when/if you choose to catch a bus, however with everyone that does, I always feel relief that their pain has finally ended. Doubt I'll ever find the testicular fortitude to go, I have so many regrets I've really become afraid to make any major life decisions. Good luck with whatever you choose, I wish you the best.
 

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