Ketamine and SN

[BadChanges]

How's the combo of SN and 200mg ketamine via injection? Is it a good combo in terms of interaction? It seems peaceful… but I'm not sure if K can interfere or not.

I can also do Fentora pills and Ketamine. It's buccal pills with like 64 percent absorption. I can have as many sd I want. I'm opioid naive.

I really need your advice. I have to go really soon.

 

[tyrcap]

This seems like a good idea

 

[Romanticize]

oh man, ket and SN is such a unique combo that not many people try.

U will be incapacitated instantly after u do 200mg ket IV -> so you need to drink Sn
SN first, then inject ket, and it will be a race against time (except if you go into the vein first, without pushing the plunger - but you risk falling out of the vein)

I see many things where it can go wrong.
Why dont you just use oral opioids and/or benzos as a support for SN?

oh, you have fentanyl - just do a massive fent dose (with or without SN). Ket doesnt cause death and its support function is debatable. Why do u want to use K so bad?

 

[BadChanges]

oh man, ket and SN is such a unique combo that not many people try.

U will be incapacitated instantly after u do 200mg ket IV -> so you need to drink Sn
SN first, then inject ket, and it will be a race against time (except if you go into the vein first, without pushing the plunger - but you risk falling out of the vein)

I see many things where it can go wrong.
Why dont you just use oral opioids and/or benzos as a support for SN?

oh, you have fentanyl - just do a massive fent dose (with or without SN). Ket doesnt cause death and its support function is debatable. Why do u want to use K so bad?

Fentanyl isn't gonna work with SN.

I inject Ket IM. Not IV. I can drop the Ket.. it's not a big deal. Though I can easily inject right after ingesting SN. I think the better alternative Fentanyl, Xanax and Ketamine. That should work.

 

[gothbird]

SN and 200mg ketamine can technically be used together, yeah. They don't interact in a way that cancels each other out. SN works by turning hemoglobin into methemoglobin, so oxygen just… stops getting delivered. Ketamine won't block that. But 200mg is a deep dissociative dose, especially if you're doing it IM or IV. You might lose awareness fast, which can be a double edged sword like sure, it could dull the experience, but it also means if you vomit or miss the timing, you won't be able to react. No extra peace, just less control.

As for Fentora it is super potent. If you're opioid naive and take too much, you'll pass out or stop breathing before the SN even does its job. Again, it doesn't boost SN's effectiveness, just adds more sedation and more unpredictability. And fentanyl can cause nausea too, which makes vomiting more likely. That's a risk, especially if you're skipping proper antiemetics. I'd probably not do SN and Fent.

 

[BadChanges]

SN and 200mg ketamine can technically be used together, yeah. They don't interact in a way that cancels each other out. SN works by turning hemoglobin into methemoglobin, so oxygen just… stops getting delivered. Ketamine won't block that. But 200mg is a deep dissociative dose, especially if you're doing it IM or IV. You might lose awareness fast, which can be a double edged sword like sure, it could dull the experience, but it also means if you vomit or miss the timing, you won't be able to react. No extra peace, just less control.

As for Fentora it is super potent. If you're opioid naive and take too much, you'll pass out or stop breathing before the SN even does its job. Again, it doesn't boost SN's effectiveness, just adds more sedation and more unpredictability. And fentanyl can cause nausea too, which makes vomiting more likely. That's a risk, especially if you're skipping proper antiemetics. I'd probably not do SN and Fent.

Yeah for sure. I got antiemetics as well. So as an opiod naive person I should be guaranteed to pass out and die with just a few 800mcg Fentora pills, right? I can also get patches to use in conjuction with Fentora. I guess it's an overkill but I really don't wanna have any hope of staying alive.

 

[gothbird]

Yeah for sure. I got antiemetics as well. So as an opiod naive person I should be guaranteed to pass out and die with just a few 800mcg Fentora pills, right? I can also get patches to use in conjuction with Fentora. I guess it's an overkill but I really don't wanna have any hope of staying alive.

800mcg Fentora is a strong dose, especially if you're opioid naive. Fentanyl is insanely potent like, microgram level potent and buccal tablets like Fentora have high absorption (around 60–65%), so yeah, I think you'd be pretty dead.
Also, patches release fentanyl slowly over time they're made for steady, controlled delivery over 48–72 hours. So adding them does increase the total load, but it won't push you over the edge quickly. They're more of a background effect than a knockout.

If you're looking for no fail and no wake up, SN (with proper fasting and antiemetics) still has a far better track record when done correctly.

 

[BadChanges]

800mcg Fentora is a strong dose, especially if you're opioid naive. Fentanyl is insanely potent like, microgram level potent and buccal tablets like Fentora have high absorption (around 60–65%), so yeah, I think you'd be pretty dead.
Also, patches release fentanyl slowly over time they're made for steady, controlled delivery over 48–72 hours. So adding them does increase the total load, but it won't push you over the edge quickly. They're more of a background effect than a knockout.

If you're looking for no fail and no wake up, SN (with proper fasting and antiemetics) still has a far better track record when done correctly.

You think that it's a better option than Fentora and Xanax for someone like me?

 

[Romanticize]

what do you mean fentanyl will not work with SN? its a good combo, both are working on respiration (different mechanisms but fent slows down breathing and SN makes breathing inefficient) so its a good combo. The only downside is that fent causes vomiting, but SN will make you vomit too.

As you I would do massive fent+benzo dose, and as a secondary option SN (+benzo ofc).
Ket is kinda useless if you have benzos

 

[gothbird]

You think that it's a better option than Fentora and Xanax for someone like me?

Honestly? Yeah, probably.
Fentora + Xanax sounds strong, especially if you're opioid and benzo naive. Both drugs are central nervous system depressants like they slow breathing, heart rate, all that but taken orally (even sublingual or buccal), they still have a chance of not fully doing the job. You could pass out, sure, but not necessarily die. A lot of people wake up in hospitals after taking huge amounts of both. It's not a guaranteed exit, especially if someone finds you or if your body metabolizes it weirdly.

SN, on the other hand, works by a completely different mechanism. It causes methemoglobinemia, which basically blocks your blood from carrying oxygen. It has a more predictable progression, especially if you fast, take proper antiemetics (like meto or domperidone), and dose it right. If everything is set up properly, SN is clinically more consistent in terms of both timing and outcome.

what do you mean fentanyl will not work with SN? its a good combo, both are working on respiration (different mechanisms but fent slows down breathing and SN makes breathing inefficient) so its a good combo. The only downside is that fent causes vomiting, but SN will make you vomit too.

As you I would do massive fent+benzo dose, and as a secondary option SN (+benzo ofc).
Ket is kinda useless if you have benzos

Yeah I get what you're saying, but it's not that fentanyl + SN "won't work," it's just that they don't help each other in the way people sometimes assume. They both act on respiration, but totally differently like fentanyl suppresses breathing by acting on the brainstem basically telling your body to slow or stop breathing and SN causes methemoglobinemia so your blood still moves oxygen around mechanically, but the hemoglobin can't bind or deliver it. So you breathe, but your cells suffocate anyway.

So technically, yeah, both are targeting oxygen delivery but in non synergistic ways. Fent won't make SN more effective. If anything, stacking them can add unpredictability, especially if fent kicks in too hard before the SN is absorbed, or causes you to vomit and can't take the second drink. That's the main risk I suppose. loss of control. I just worry about that. There just isn't enough research/examples to feel good to recommend.

 

[Romanticize]

thats what i said, opioids dont potentiate SN directly like other CNS depressants do, but they further lower the respiration rate, and both of them can be easily lethal, I would even rate fent+SN as a complex suicide (two or more methods, lethal on their own). Vomiting would still occur (SN makes you vomit much more often than opioids, I take opioids daily for 7 years and vomited twice, on my first uses and it was many hours after) so all in all I would rate SN+fent as more effective than SN alone. Like benzos are perfect support drug for almost all methods, opioids can be support drug or lethal on their own, depending on dose.

and regarding the fent+SN not working, its OP who said it, and he didnt mean the sygergy, while hes asking and believing that ket+SN would lol

 

[gothbird]

thats what i said, opioids dont potentiate SN directly like other CNS depressants do, but they further lower the respiration rate, and both of them can be easily lethal, I would even rate fent+SN as a complex suicide (two or more methods, lethal on their own). Vomiting would still occur (SN makes you vomit much more often than opioids, I take opioids daily for 7 years and vomited twice, on my first uses and it was many hours after) so all in all I would rate SN+fent as more effective than SN alone. Like benzos are perfect support drug for almost all methods, opioids can be support drug or lethal on their own, depending on dose.

and regarding the fent+SN not working, its OP who said it, and he didnt mean the sygergy, while hes asking and believing that ket+SN would lol

Right, so just to untangle a bit of this because I think we are getting lost in communication.

You're not wrong that fentanyl and SN both affect oxygen delivery, but it's important to understand that they don't actually amplify each other's effects in the way true synergistic combos do. Like yeah fentanyl slows your breathing, and SN makes the oxygen you do breathe basically useless to your cells so like different mechanisms, same endpoint: hypoxia. But stacking them doesn't guarantee anything, it just adds more layers of risk. That's what I'm worried about.

The biggest issue with fent + SN is timing and control. Fent can knock you out fast, especially if you're opioid naive. That sounds good on paper, but if you go out before you vomit and can't re dose then you've lost your window and might survive. That's what I'm trying to say.

Pretty sure the pph only briefly mentions fentanyl mostly just that it's potent but unreliable for self delivery due to patch slow release, buccal absorption issues, and high risk of survival if the dose or timing is off. I'm going off memory though, not at my PC!

 

[BadChanges]

Right, so just to untangle a bit of this because I think we are getting lost in communication.

You're not wrong that fentanyl and SN both affect oxygen delivery, but it's important to understand that they don't actually amplify each other's effects in the way true synergistic combos do. Like yeah fentanyl slows your breathing, and SN makes the oxygen you do breathe basically useless to your cells so like different mechanisms, same endpoint: hypoxia. But stacking them doesn't guarantee anything, it just adds more layers of risk. That's what I'm worried about.

The biggest issue with fent + SN is timing and control. Fent can knock you out fast, especially if you're opioid naive. That sounds good on paper, but if you go out before you vomit and can't re dose then you've lost your window and might survive. That's what I'm trying to say.

Pretty sure the pph only briefly mentions fentanyl mostly just that it's potent but unreliable for self delivery due to patch slow release, buccal absorption issues, and high risk of survival if the dose or timing is off. I'm going off memory though, not at my PC!

Hey. I managed to get a gold of Fentanyl intranasal spray. It has 8 squirts and each one contains 400mcg of Fentanyl. I can get as many as I need. Apparently it has 90% bioavailability. What do you say? is it good enough?

I can add Fentora and the sublingual fentanyl as well. And as many Xanax as I want. There is someone who knows of my wishes to die and doesn' want me to use SN because she doesn't want me to suffer.