Discussion I have Midazolam, rocuronium and might get propofol too.....

[thedivine]

i can easily get a cannula from a clinic/small hospital. and a drip or anything else needed
Q.1 . how can someone administer 100ml of propofol under 5mins ? , i mean even if someone else do it there's no way 100 ml is going in veins under 5min without any problem
Q.2. Will only Midaz and Rocuronium be peaceful? if i dont get propofol?

Thanks

 

[Sunset Limited]

First, you need information about the anesthesia induction dose of midazolam. That is, what is the dose of midazolam needed to intubate a patient, providing the depth of surgical anesthesia? If we take the upper limit, it's 0.35 mg/kg. Your height and weight are important. At this dose, you are completely unconscious.

What form of midazolam do you have? 0.1% or 0.5%? If it's 0.5%, that's good news, it means faster injection. Assuming you weigh 70 kg, the anesthesia induction dose for you would be 24.5 mg. That's 5 cc of medication. If it's 0.1%, that's 25 cc.

The good news is that midazolam injections aren't as painful as propofol and thiopental. The bad news is that midazolam's effect is quite specific. Very different doses may be needed to achieve the depth of surgical anesthesia with midazolam. Whether it produces as deep sedation as propofol and thiopental is debatable. Rocuronium injections are painful, but not as much as propofol. The onset time for midazolam to induce deep surgical anesthesia and the onset time for rocuronium to paralyze the diaphragm muscle are similar, 60-90 seconds.

While your plan seems feasible, the only problem is midazolam's poor reputation for deep sedation. If you try to do this with propofol, things will become more complicated. Thiopental + rocuronium would be the best option, as thiopental is available in powder form in a vial.