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mordumfan

mordumfan

lizzie //
Aug 12, 2025
40
Can someone who uses them tell me if they do anything, I am very jealous of people who have them prescribed. There is a girl I know who isn't suicidal (not even before she was prescribed them) or depressed. I'm not shaming her at all, I'm just mad because I can't get them when I feel like I desperately need them. Can someone tell me about their personal experiences with anti depressants and if I should keep trying to get them?
 
NutOrat

NutOrat

Falling Down
Jun 11, 2025
305
They haven't worked for me so far, 1 and a half month almost nothing will help me. But they work for other people I think I'm just beyond help no pill will make me want to move.
 
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OnMyLast Legs

OnMyLast Legs

Too many regrets
Oct 29, 2024
1,068
I think long term your life has to change but they can stop the worst of the worst. When you're bedrotting and your body feels tight and sore and you just can't do anything drugs can help break that.
 
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LastNite

LastNite

Hello World
Mar 31, 2025
542
Heres a list of antidepressants that Ive tried: Prozac, Mirtazapine, Wellbutrin, Zofolt, Lexapro, Cymbalta, Trazodone, and uh I think thats It? I could be wrong maybe missed one or two. But overall experience terrible.

Some side effects Ive experienced with some of these include extreme appetite & no change to depression (Mirtazapine), Constant headaches & Feeling drowsy & no change to depression (Trazodone), brain zaps and pain from withdrawals & no change to depression (Cymbalta). Im pretty sure I missed a few because Ive been trying different ones for well over a year.

Prozac made me feel numb emotionally. I didnt like it. Zofolt which Im currently on uhh Im not exactly sure. I guess I feel ok? I dont think the dose is good though it's 25mg Im planning on trying to increase it after my appointment.

Im impatient btw so my experience is rushed meaning if it didnt work I dont try to increase the dose. For every single drug I mentioned my doc asked me if Im willing to increase the dose to see if it helps and I said no Id like to try something different.
If all else fails Im just gonna do ketamine therapy. It treats people with treatment resistant depression which Im starting to think I got. I wish you the best I hope my input helped. Also please research yourself on what antidepressants you might hate to try. Im not saying dont try it im just saying if your sensitive to pain then be careful with cymbalta & some other hard-to-quit antidepressants because if it doesnt work then quitting alone hurts. The brain zaps are like headache but with electricity and double the pain. When I tried to quit it my doc didnt help me taper off (lean off it) slowly. So I basically quit cold turkey.
 
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mordumfan

mordumfan

lizzie //
Aug 12, 2025
40
They haven't worked for me so far, 1 and a half month almost nothing will help me. But they work for other people I think I'm just beyond help no pill will make me want to move.
Thanks for the response, I'm starting to doubt it would work for me
Heres a list of antidepressants that Ive tried: Prozac, Mirtazapine, Wellbutrin, Zofolt, Lexapro, Cymbalta, Trazodone, and uh I think thats It? I could be wrong maybe missed one or two. But overall experience terrible.

Some side effects Ive experienced with some of these include extreme appetite & no change to depression (Mirtazapine), Constant headaches & Feeling drowsy & no change to depression (Trazodone), brain zaps and pain from withdrawals & no change to depression (Cymbalta). Im pretty sure I missed a few because Ive been trying different ones for well over a year.

Prozac made me feel numb emotionally. I didnt like it. Zofolt which Im currently on uhh Im not exactly sure. I guess I feel ok? I dont think the dose is good though it's 25mg Im planning on trying to increase it after my appointment.

Im impatient btw so my experience is rushed meaning if it didnt work I dont try to increase the dose. For every single drug I mentioned my doc asked me if Im willing to increase the dose to see if it helps and I said no Id like to try something different.
If all else fails Im just gonna do ketamine therapy. It treats people with treatment resistant depression which Im starting to think I got. I wish you the best I hope my input helped. Also please research yourself on what antidepressants you might hate to try. Im not saying dont try it im just saying if your sensitive to pain then be careful with cymbalta & some other hard-to-quit antidepressants because if it doesnt work then quitting alone hurts. The brain zaps are like headache but with electricity and double the pain. When I tried to quit it my doc didnt help me taper off (lean off it) slowly. So I basically quit cold turkey.
that sounds like it sucks ASS. Thanks for the response tho, looks like ill just ctb or find something else
 
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NutOrat

NutOrat

Falling Down
Jun 11, 2025
305
I'm sorry no-one should ever listen to me. Don't take what I said seriously.
 
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VoidButterfly

VoidButterfly

Flitterby
May 17, 2025
146
They do work, but they aren't miracles and they certainly won't all work for you, it'll be a process to find what works unless you get lucky. I cycled through so many of them.
  • I found SSRIs the least effective, I went through several and experienced everything from nothing to throwing up blood. Sertraline was the best of them for me, it felt like it took the edge off the depression. It certainly didn't fix it, but it made it slightly more tolerable.
  • Then I was on mirtazapine, that's a NASSA (Noradrenaline and specific serotonergic antidepressant) and it was good for anxiety and I stayed on that one for a while.
  • They put me on an SNRI (Serotonin-noradrenaline reuptake inhibitors) called venlafaxine which made me manic as fuck (I'm bipolar). I dunno how that'd work for normal people but it definitely improved my mood lol. I was literally dancing in the street, but unfortunately I also went to work and deleted my code and rewrote it using a hypothesis about prime numbers I developed whilst being unable to sleep.
Anyways, I'm currently on vortioxetine which is a SMS (serotonin modulator and stimulator) and I'd say it helps. When they also added an antipyschotic I genuinely did feel more stable for a long while, it took away the lows but unfortunately also the highs. But then the world made my life infinitely more shit and now I barely even bother taking them. If your life has any hope whatsoever of getting better, I'd say antidepressants are a tool that'll help you get there rather than the fix themselves, if you can find one that works for you.
 
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mordumfan

mordumfan

lizzie //
Aug 12, 2025
40
They do work, but they aren't miracles and they certainly won't all work for you, it'll be a process to find what works unless you get lucky. I cycled through so many of them.
  • I found SSRIs the least effective, I went through several and experienced everything from nothing to throwing up blood. Sertraline was the best of them for me, it felt like it took the edge off the depression. It certainly didn't fix it, but it made it slightly more tolerable.
  • Then I was on mirtazapine, that's a NASSA (Noradrenaline and specific serotonergic antidepressant) and it was good for anxiety and I stayed on that one for a while.
  • They put me on an SNRI (Serotonin-noradrenaline reuptake inhibitors) called venlafaxine which made me manic as fuck (I'm bipolar). I dunno how that'd work for normal people but it definitely improved my mood lol. I was literally dancing in the street, but unfortunately I also went to work and deleted my code and rewrote it using a hypothesis about prime numbers I developed whilst being unable to sleep.
Anyways, I'm currently on vortioxetine which is a SMS (serotonin modulator and stimulator) and I'd say it helps. When they also added an antipyschotic I genuinely did feel more stable for a long while, it took away the lows but unfortunately also the highs. But then the world made my life infinitely more shit and now I barely even bother taking them. If your life has any hope whatsoever of getting better, I'd say antidepressants are a tool that'll help you get there rather than the fix themselves, if you can find one that works for you.
Thank you for this information! Can I also ask if you had any other permanent side effects from taking these? Because my parents were always super against them because they have 'dangerous side effects', and I wanna hear from someone who has actually taken them if its true.
 
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OnMyLast Legs

OnMyLast Legs

Too many regrets
Oct 29, 2024
1,068
I think long term your life has to change but they can stop the worst of the worst. When you're bedrotting and your body feels tight and sore and you just can't do anything drugs can help break that.
Wellbutrin seems to be the one working sort of well (I'm on a stack of Rx drugs right now)
 
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C

carfemtanyl

Member
Nov 18, 2025
82
I've been on Sertraline/Zoloft for 4 years now and for me, it reduced my dreadful look into the future. Before I took it, I had immense anxiety and dread whenever I thought about the future but now it kinda numbs that away. I also don't feel that much in general while I'm on it but whenever I try to get off it, I'm immediately hit with a bunch of strong negative emotions like the world is ending.
 
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F

Forveleth

I knew I forgot to do something when I was 15...
Mar 26, 2024
3,415
There are two things to know about antidepressants. The first is that every single one acts differently for different people. For example, Lexapro might be great for one person and terrible for another. Some people have to go through a dozen antidepressants before they find one that works. So they can work, it just takes some effort to find the right drug.

The second thing is that antidepressants do not actually solve your problems. A lot of people think taking the pill will magically make your life better. That is not how they work. What they do is kick you out of the mental funk you are in so that you are more receptive to things like therapy and life changes that can help you improve your situation. So in that way, antidepressants alone do not solve your problems, but are rather part of an overall tool set.
 
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VoidButterfly

VoidButterfly

Flitterby
May 17, 2025
146
Thank you for this information! Can I also ask if you had any other permanent side effects from taking these? Because my parents were always super against them because they have 'dangerous side effects', and I wanna hear from someone who has actually taken them if its true.

I haven't had any permanent side effects that I'm aware of, but there really can be side effects. Some people experience long term sexual dysfunction, there's links to diabetes and heart disease too for people over 30. For some people they can make you more suicidal whch obviously can have its own consequences so you have to be careful about watching for that. And there's just a whole host of random side effects you can experience that usually won't be long term that vary according to the individual meds. I know something a lot of people worry about is that it'll change who you are somehow, I haven't experienced that at all. So yes, lots of side effects, but then depression itself comes with a lot of them too so it's a balancing act.
 
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interna

interna

o7 o7 o7 o7
Dec 1, 2025
53
zoloft has somewhat worked for me. but i stopped taking them
 
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iamnotadinosaur:(

iamnotadinosaur:(

lost
Aug 19, 2025
54
I was on fluoxetine (i think the brand name is zactin or smth?) but it did nothing but give me awful nausea and headaches even after the side effect "adjustment time"
Now I'm on quite a large amount of sertraline (zoloft), it's prescribed for my anxiety. It does help somewhat with mitigating panic/anxiety attacks and gives me just enough energy to keep up the social charade (quite useful), but it doesn't do much at all for ideation or feeling depressed

I also think though that the expectations of antidepressants from the media is confusing everyone, because antidepressants will not make you magically turn happy and love life, but it can help you with giving back some of your ability to handle things and function. Like my meds help, but every day is still trudging through mud, just now my effort can do things instead of requiring all my effort to not go backwards.
 
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Unlucky777

Unlucky777

Specialist
Dec 10, 2025
345
For some people they work, for others they don't, and for others they make things worse. You have to try and see how you react.

Things to consider:
1. They come with lots of side effects.
2. They take a long time to start working.
3. They are only a band aid. They don't address the root cause, just mask symptoms.
4. Some may increase or intensify thoughts of CTB. For example, me, I did not have any thoughts of CTB since a teenager. Then when I started taking this stuff, I started getting lots of CTB thoughts and was actively trying to take my life.
5. For me they turned me into a zombie in conjunction with other "mood stabilizers". I did not feel like a human being. And long term use really fucked up my cognitive functionality.

An alternative to anti depressants could be ketamine therapy or TMS therapy. Me personally, ketamine therapy has been a god send and my insurance covers the treatment. I hope you get the treatment you need
 
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lawlietsph

lawlietsph

can we be done here
May 6, 2023
356
They made me feel numb which I quite liked. I am a crybaby, my soul is super sensitive, but on meds i was only crying like 4 times a year. I couldn't feel the deep sadness, neither the joy. In my opinion it was way better than feeling everything soo deeply.
The only side effect i've experienced was that I was not able to feel anything down there, no sexual desires, no orgasms, nothing.
I enjoyed it overall, and i'm actually thinking about taking them again, i just don't see the point of anything anymore.
 
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madameviolette

madameviolette

Another Big Pharma victim
Oct 9, 2025
516
Can someone who uses them tell me if they do anything, I am very jealous of people who have them prescribed. There is a girl I know who isn't suicidal (not even before she was prescribed them) or depressed. I'm not shaming her at all, I'm just mad because I can't get them when I feel like I desperately need them. Can someone tell me about their personal experiences with anti depressants and if I should keep trying to get them?
Why was she prescribe meds if she doesn't have any mental issue ?
 
kittykatt

kittykatt

Member
Mar 5, 2024
7
im on Wellbutrin for depression and Propranolol for anxiety. they have been life savers for me. id highly recommend keep trying to get some. some might not work and thats okay. its trial and error.
 
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trashisland

trashisland

outsider
Aug 5, 2025
136
Can someone who uses them tell me if they do anything, I am very jealous of people who have them prescribed. There is a girl I know who isn't suicidal (not even before she was prescribed them) or depressed. I'm not shaming her at all, I'm just mad because I can't get them when I feel like I desperately need them. Can someone tell me about their personal experiences with anti depressants and if I should keep trying to get them?
no they didnt work and I stopped taking them. they made me worse actually. before my mood was something id describe as empty and thats been the case for years, but when I was on them I was noticeably depressed. like sad feeling and really upset a lot, more suicidal too and very hopeless. it had no positive changes on my mood. side effects were bad too, restlessness was so bothersome it annoyed me every moment of the day and it didnt help with my already existing sleep issues. now that ive stopped I am empty again but at least I am not feeling like that. id rather feel nothing at all than whatever that was. for reference I only took them for like 3 or so months which isnt the longest but I was seeing zero improvements even with dosage increases so I quit

but if you want them and genuinely think they might help, you should try. everyone is different and my experience might not be like yours. if they dont help then you can always stop or get switched to something else too
 
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coldworld

coldworld

Member
Dec 25, 2025
31
I took sertraline for 3 years and it stopped me from getting anxiety attacks, dissociating, and cutting myself, but i didnt like the way it made me feel so numb like not sad but not happy either, i didnt feel like myself at all. so I recently stopped taking them and just take vyvanse (adhd medication) instead.
 
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OnMyLast Legs

OnMyLast Legs

Too many regrets
Oct 29, 2024
1,068
im on Wellbutrin for depression and Propranolol for anxiety. they have been life savers for me. id highly recommend keep trying to get some. some might not work and thats okay. its trial and error.
I'm having a good experience with those two. Sort of. I can't really blame chemicals for my suicidal thoughts given the objective state of my life.
 
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B

BlockedintheUK

Member
Dec 20, 2025
95
Can someone who uses them tell me if they do anything, I am very jealous of people who have them prescribed. There is a girl I know who isn't suicidal (not even before she was prescribed them) or depressed. I'm not shaming her at all, I'm just mad because I can't get them when I feel like I desperately need them. Can someone tell me about their personal experiences with anti depressants and if I should keep trying to get them?
they work for some people for sure and there are many different types. 1oo% try to get them and try a number of different ones before giving up there is nothing to lose.

Some people get no improvement some get mild improvement some get huge improvement. Try a number of different types.

Why cant you get them? If money is an issue you can get them crazy cheap from India.
Thank you for this information! Can I also ask if you had any other permanent side effects from taking these? Because my parents were always super against them because they have 'dangerous side effects', and I wanna hear from someone who has actually taken them if its true.
Get medical advise from a doctor NOT from your parents they are ignorant with all due respect. Even if they were doctors it would be unethical for them to treat their child.

I would be tempted to tell them do you know what else has a "dangerous side effect"? Being dead!
Are you certain that girl wasnt depressed @mordumfan ? She should have been prescribed them if she wasnt.

Remember that people are great at hiding this shit and if you ask her she may simply not want to admit it.

I dont see any benefit or reason to take it if you arent depressed or anxious.
 
Last edited:
mordumfan

mordumfan

lizzie //
Aug 12, 2025
40
they work for some people for sure and there are many different types. 1oo% try to get them and try a number of different ones before giving up there is nothing to lose.

Some people get no improvement some get mild improvement some get huge improvement. Try a number of different types.

Why cant you get them? If money is an issue you can get them crazy cheap from India.

Get medical advise from a doctor NOT from your parents they are ignorant with all due respect. Even if they were doctors it would be unethical for them to treat their child.

I would be tempted to tell them do you know what else has a "dangerous side effect"? Being dead!
Are you certain that girl wasnt depressed @mordumfan ? She should have been prescribed them if she wasnt.

Remember that people are great at hiding this shit and if you ask her she may simply not want to admit it.

I dont see any benefit or reason to take it if you arent depressed or anxious.
Honestly im pretty sure she's not depressed, but she could be hiding it for all i know, i probably shouldnt just assume shes not. I don't think my parents could care less, they despite anti depressants, i remember specifically in 2024 when I saw a doctor and my mother just straight told her "we don't like anti depressants"

I could dm you the reason I can't get them, if you want?

Im thinking about ctb tonight, i was supposed to do it yesterday but had probably the worst headache ive head in a while (excuses excuses i know)

Thanks for the reply aswell
 
B

BlockedintheUK

Member
Dec 20, 2025
95
Honestly im pretty sure she's not depressed, but she could be hiding it for all i know, i probably shouldnt just assume shes not. I don't think my parents could care less, they despite anti depressants, i remember specifically in 2024 when I saw a doctor and my mother just straight told her "we don't like anti depressants"

I could dm you the reason I can't get them, if you want?

Im thinking about ctb tonight, i was supposed to do it yesterday but had probably the worst headache ive head in a while (excuses excuses i know)

Thanks for the reply aswell
Yes please feel free to DM me my DMs are always open.

I have no idea why someone would use antidepressants if they wernt depressed and they would have to lie to a doctor to get them. I would assume she is depessed and just hiding it. Many times someone decided to CTB and no one know they had any kind of problem
 

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