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manchuman123

Member
Aug 10, 2025
25
Ive been on other antidepressants, lexapro, prozac, and not Zoloft, and they want to start me on wellbutrin too. Since starting zoloft, I feel like it just washed a little bit of the guilt. Maybe I'm just running on autopilot, and my desire to be free? Is it worth going on more antidepressants, like,e honestly? But honestly, I don't want to feel better; weirdly enough, I feel mentally clearer than ever.
 
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Eriktf

Mage
Jun 1, 2023
513
its worth a try it might help you.

i have tryed all lot of different meds and some especially SSRI have made me worse but after some trying i did find a combo of meds that works
 
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real human being

real human being

full of broken thoughts
Jan 28, 2022
230
Antidepressants can cause long term issues. It can be extremely difficult to keep taking them after a while due to withdrawal symptoms. They can cause sexual dysfunction, emotional numbing, and physical issues as well. Some effects may last long term even after you quit taking them.

Wellbutrin is a benzodiazipine. They're very addictive and dangerous.

Don't blindly trust psychiatry.
 
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roommate

roommate

Trying to drag myself out of the garbage
Feb 14, 2025
442
Antidepressants can cause long term issues. It can be extremely difficult to keep taking them after a while due to withdrawal symptoms. They can cause sexual dysfunction, emotional numbing, and physical issues as well. Some effects may last long term even after you quit taking them.

Wellbutrin is a benzodiazipine. They're very addictive and dangerous.

Don't blindly trust psychiatry.
How onnuanced is this comment!
Medication is tested, ofcourse there are risks, but with a good psychiatry the risks would be weighted.
 
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orpheus_

orpheus_

Member
Apr 26, 2024
46
Wellbutrin is a benzodiazipine
It's not. Actually quite the opposite. It contains bupropion, which influences noradrenaline and dopamine - usually works by improving energy and motivation. Benzos are sedating meds, prescribed for people with anxiety issues. Also bupropion is known to be one of the easiest antidepressants to come off of as it doesn't have many withdrawal effects.

I agree that blindly trusting a doctor may be dangerous BUT research about meds is mostly legit. Read about how they work, the most common side effects etc.
Everyone has VERY individual reactions but there are some statistical averages.

All of the meds you mentioned are SSRIs. If they don't work for you, maybe a different class of drugs can be successful. For example SNRIs (like duloxetine or venlafaxine), or tricyclic antidepressants (though the latter are a last resort really because they often have unpleasant side effects).

Wellbutrin is not a SSRI but a NDRi, It works differently than the ones you've taken before, so it might be worth giving it a shot - but it's mostly helpful if you have the low energy, apathetic kind of depression. It can worsen anxiety if you have problems with that.
 
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real human being

real human being

full of broken thoughts
Jan 28, 2022
230
How onnuanced is this comment!
Medication is tested, ofcourse there are risks, but with a good psychiatry the risks would be weighted.
Antidepressants are prescribed like candy. It's not a weighted risk, it's a greatly underestimated and underaknowledged risk
It's not. Actually quite the opposite. It contains bupropion, which influences noradrenaline and dopamine - usually works by improving energy and motivation. Benzos are sedating meds, prescribed for people with anxiety issues. Also bupropion is known to be one of the easiest antidepressants to come off of as it doesn't have many withdrawal effects.

I agree that blindly trusting a doctor may be dangerous BUT research about meds is mostly legit. Read about how they work, the most common side effects etc.
Everyone has VERY individual reactions but there are some statistical averages.

All of the meds you mentioned are SSRIs. If they don't work for you, maybe a different class of drugs can be successful. For example SNRIs (like duloxetine or venlafaxine), or tricyclic antidepressants (though the latter are a last resort really because they often have unpleasant side effects).

Wellbutrin is not a SSRI but a NDRi, It works differently than the ones you've taken before, so it might be worth giving it a shot - but it's mostly helpful if you have the low energy, apathetic kind of depression. It can worsen anxiety if you have problems with that.
My bad, I confused waben with wellbutrin.

But my point regarding the risks of a lot of these psychiatric medications stands. Google PSSD (Post SSRI Sexual Dysfunction).
 
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roommate

roommate

Trying to drag myself out of the garbage
Feb 14, 2025
442
Antidepressants are prescribed like candy. It's not a weighted risk, it's a greatly underestimated and underaknowledged risk

My bad, I confused waben with wellbutrin.

But my point regarding the risks of a lot of these psychiatric medications stands. Google PSSD (Post SSRI Sexual Dysfunction).
I did Google and found that it is estimated a 0.46% risk.
Even anticonception is more risky to use for it's intent if we can put it on the scale.
But yeah OP, listen to your doctor (a real expert) not to randoms on this forum.
 
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Ashu

Ashu

novelist, sanskritist, Canadian living in India
Nov 13, 2021
821
How onnuanced is this comment!
Medication is tested, ofcourse there are risks, but with a good psychiatry the risks would be weighted.
Yeah. "Doctor, your drug ravaged my body and soul and permanently destroyed my sexuality. Now I wanna die even more." Doctor: "Well, there are more important things than sex, and life can be beautiful - just ask me, a normy. Here's a fistful of very effective antidepressants to help you realize that."
 
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real human being

real human being

full of broken thoughts
Jan 28, 2022
230
I did Google and found that it is estimated a 0.46% risk.
Even anticonception is more risky to use for it's intent if we can put it on the scale.
But yeah OP, listen to your doctor (a real expert) not to randoms on this forum.
0.46% so a roughly 1 in 200 chance of getting long-term/permanent sexual dysfunction. That is a pretty significant risk and it's only one of the risks when it comes to antidepressants.

You're using an appeal to authority but you should remember not too long ago psychiatrists did lobotomies for women diagnosed with hysteria so medical professionals can certainly be wrong and I for one think psychiatry as a profession is utterly broken. Meds only mask the symptoms of mental illnesses in almost all cases rather than dealing with the root cause and they're often the first and only resort of psychiatrists.
 
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