FadingSnowFake
Enlightened
- Nov 25, 2024
- 1,068
I obtained Ondansetron 8mg (as HCl – 2H2O, drug name Onsia) in the place of meto, and Diphenhydramine HCl 50mg (drug name PHeNZ, a sleep aid) in place of benzos. Apologies if I'm repeating questions, as I'm confused about what may or may not work with SN. I would like to test the meds next weekend and would appreciate your thoughts.
In my mind, a solid anti-emetic is more important than a relaxing sedative, since we want to prevent vomiting but a sedative to calm the nerves can also be helpful. It appears ondansetron may also cause drowsiness, then perhaps it could be used as anti-emetic and sedative? I doubt diphenhydramine could alleviate nausea caused by SN, but some "individuals with emetophobia (fear of vomiting) found that it helps settle their stomach and reduces anxiety related to nausea." I'd rather leave something which may cause an unwanted reaction but ideally want to take something in the place of both benzos and meto.
More from Google:
1. Meto vs ondansetron: it appears metos are the only "GI stimulant", but ondansetron is "sometimes prescribed off-label for conditions such as nausea and vomiting during gastroenteritis." Metoclopramide works by blocking dopamine D2 receptors in the brain, which helps to reduce nausea and vomiting. It also enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying without increasing gastric acid secretion.
Ondansetron works by blocking the action of serotonin, a neurotransmitter that can induce nausea and vomiting when it binds to specific receptors in the brain and gastrointestinal tract. By inhibiting these receptors, ondansetron reduces the sensation of nausea and prevents vomiting. Side effects may include headache, dizziness, fatigue, constipation, and drowsiness.
2. Benzos vs Diphenhydramine: Benzodiazepines are used to treat anxiety disorders, insomnia, and seizures. They work by slowing down activity in the brain and nervous system, which can help alleviate symptoms of anxiety and promote sleep.
Diphenhydramine is used as a short-term treatment for insomnia, helping individuals fall asleep more easily. It can be an effective treatment for nausea, particularly in cases of motion sickness or anxiety-related nausea. However, there is the possibility of experiencing nausea itself (high doses) and it can cause an upset stomach.
Thanks for your time.
In my mind, a solid anti-emetic is more important than a relaxing sedative, since we want to prevent vomiting but a sedative to calm the nerves can also be helpful. It appears ondansetron may also cause drowsiness, then perhaps it could be used as anti-emetic and sedative? I doubt diphenhydramine could alleviate nausea caused by SN, but some "individuals with emetophobia (fear of vomiting) found that it helps settle their stomach and reduces anxiety related to nausea." I'd rather leave something which may cause an unwanted reaction but ideally want to take something in the place of both benzos and meto.
More from Google:
1. Meto vs ondansetron: it appears metos are the only "GI stimulant", but ondansetron is "sometimes prescribed off-label for conditions such as nausea and vomiting during gastroenteritis." Metoclopramide works by blocking dopamine D2 receptors in the brain, which helps to reduce nausea and vomiting. It also enhances gastrointestinal motility by increasing the tone of the lower esophageal sphincter and accelerating gastric emptying without increasing gastric acid secretion.
Ondansetron works by blocking the action of serotonin, a neurotransmitter that can induce nausea and vomiting when it binds to specific receptors in the brain and gastrointestinal tract. By inhibiting these receptors, ondansetron reduces the sensation of nausea and prevents vomiting. Side effects may include headache, dizziness, fatigue, constipation, and drowsiness.
2. Benzos vs Diphenhydramine: Benzodiazepines are used to treat anxiety disorders, insomnia, and seizures. They work by slowing down activity in the brain and nervous system, which can help alleviate symptoms of anxiety and promote sleep.
Diphenhydramine is used as a short-term treatment for insomnia, helping individuals fall asleep more easily. It can be an effective treatment for nausea, particularly in cases of motion sickness or anxiety-related nausea. However, there is the possibility of experiencing nausea itself (high doses) and it can cause an upset stomach.
Thanks for your time.
