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kaleisgreatinsalad

Member
Mar 17, 2025
10
About four years ago, I started taking Lexapro (20mg). Within a few months, I felt extremely suicidal, depressed, and anxious. I had never been suicidal before taking an SSRI—I only had mild anxiety, but my doctor insisted this medication would help. When I told him it was making me suicidal, he added Effexor at the highest dose.

This combination caused genital numbness and made me so suicidal that I began researching assisted suicide. I begged my doctor to let me stop, but he told me to keep taking it. I quit cold turkey, and thankfully, the numbness went away, and I stabilized. But the suicidal thoughts lingered.

A year later, I tried Zoloft. The same thing happened—this time with memory problems, depersonalization, and such severe panic attacks that I couldn't even drink coffee. I stayed on it for another year before quitting last January. At first, I felt better—my anxiety was still there, but the suicidal thoughts faded.

Then, after a family crisis and a sleepless night, I started getting brain shocks. For three months, I barely slept, and my anxiety became so extreme that my hair fell out. A doctor prescribed an antipsychotic, which made me lose even more hair (all over my body) and turned me into a zombie. I quit after two weeks.

Hospitalized and desperate, I was forced onto a mood stabilizer and Zoloft again. The suicidal thoughts returned. My parents made me try Cymbalta, which left me sleepless for five days, completely numb genitally, and with such bad brain fog and memory issues that I'd go to fill up my car and pay for gas, then drive away without filling up. My brain burned constantly, like it was on fire. I quit cold turkey again.

Now, a year later, I'm a shell of myself. I feel no emotions—no joy from music, no love for my family (though I know I love them), no runner's high. I used to be passionate and full of life; now, I'm empty. I am starting to lose hope that I can continue to live life like this. I should also add that I have been on no medication for over a year now. I still to this day have numb genitals and a lack of orgasms. I cannot feel joy or sadness in any form. Cymbalta took my soul and sense of self and my pleasure.
 
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SomewhatLoved

SomewhatLoved

all bleeding stops eventually...
Apr 12, 2023
374
This is awful. This whole thing was caused by your doctor not listening to you or taking into account your experience and opinions.

I'm so sorry that this has happened to you. From the information you give, it seems like before this all started you were a (at least mostly) happy person. Sometimes recovery can be a long road, but for you there might be something at the end of the tunnel!

I'm sure you have a lot of distrust for healthcare practitioners now, as any sane person would after having gone through what you did. Are you at all interested in getting mental health supports? Therapy?
 
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kaleisgreatinsalad

Member
Mar 17, 2025
10
This is awful. This whole thing was caused by your doctor not listening to you or taking into account your experience and opinions.

I'm so sorry that this has happened to you. From the information you give, it seems like before this all started you were a (at least mostly) happy person. Sometimes recovery can be a long road, but for you there might be something at the end of the tunnel!

I'm sure you have a lot of distrust for healthcare practitioners now, as any sane person would after having gone through what you did. Are you at all interested in getting mental health supports? Therapy?
Yes, a very bad situation. He wouldn't listen to me and I appreciate what you've said. Before this, I had never been depressed in my life. I had never been suicidal before until a few weeks into taking Lexapro. And I have tried multiple times, it's hard to do therapy when you cannot feel or process your emotions. PSSD is much different than something like depression or anxiety its like the absence of all emotions. I haven't cried in over a year which is very weird for me. I tried therapy but I was dismissed for my issues multiple times. When I was diagnosed by a urologist with this condition that antidepressants can cause long-term genial numbness and anorgasmia. I have spoken with a lady whose had this condition for 30 years. She however was lucky enough is it even can be considered that to only have the sexual side effects she still can feel emotions. I have both numbness in my privates and numbed out emotionally.
 
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FuneralCry

FuneralCry

Just wanting some peace
Sep 24, 2020
43,526
That sounds really dreadful to me, I'm sorry you have to suffer, it's so cruel to me how there's all this suffering in existing with no limit as to how unbearable it can get, I wish you the best.
 
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Bad Ending

Bad Ending

Anhedonia and PSSD sufferer
Mar 16, 2025
84
I have it and It ruined my life too, I have to ctb because of it 😞
 
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SomewhatLoved

SomewhatLoved

all bleeding stops eventually...
Apr 12, 2023
374
Yes, a very bad situation. He wouldn't listen to me and I appreciate what you've said. Before this, I had never been depressed in my life. I had never been suicidal before until a few weeks into taking Lexapro. And I have tried multiple times, it's hard to do therapy when you cannot feel or process your emotions. PSSD is much different than something like depression or anxiety its like the absence of all emotions. I haven't cried in over a year which is very weird for me. I tried therapy but I was dismissed for my issues multiple times. When I was diagnosed by a urologist with this condition that antidepressants can cause long-term genial numbness and anorgasmia. I have spoken with a lady whose had this condition for 30 years. She however was lucky enough is it even can be considered that to only have the sexual side effects she still can feel emotions. I have both numbness in my privates and numbed out emotionally.
Was the person who you spoke to who also has PSSD able to do anything to improve their symptoms? I imagine this is probably quite a niche condition, but I wonder if maybe there are support groups or peer resources you could try accessing?
 
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Pale_Rider

Pale_Rider

Wizard
Apr 21, 2025
677
Agreed.
I read that wrong. I read PTSD. sorry/
 
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kaleisgreatinsalad

Member
Mar 17, 2025
10
That sounds really dreadful to me, I'm sorry you have to suffer, it's so cruel to me how there's all this suffering in existing with no limit as to how unbearable it can get, I wish you the best.
I am sorry to suffer as well. The past 4 years have been a nightmare and this past year is like living a daily hell. I cannot describe how awful this is, to wake up one day unable to feel love for your own family. To see your mother as a stranger and no longer feel love for them is a pain I wouldn't wish on anyone. It has taken everything in me to still be alive.
I have it and It ruined my life too, I have to ctb because of it 😞
I am sorry, it is a tragedy. How long have you had PSSD for if you don't mind me asking? And I am not familiar with ctb. What is that?
Was the person who you spoke to who also has PSSD able to do anything to improve their symptoms? I imagine this is probably quite a niche condition, but I wonder if maybe there are support groups or peer resources you could try accessing?
She said she often contemplated suicide and it took years for her to eventually develop a relationship emotionally and build a successful life of research into the condition and spread awareness of PSSD. She told me to try and look for moments I don't notice the PSSD to look for support from family and friends for help. I have been in a support group for PSSD for several months now but I still struggle to keep living. We all share how we feel regularly and check in with each other but living life without emotions or sexual feelings and numb genitals will be very hard to keep going with. I have considered meeting with therapists that are aware of PSSD but it has been hard to find any. I don't wanna sound negative but this is the reality for me but I loved my life before all this happened. Thank you for responding I appreciate your advice.
 
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sick&tired

sick&tired

Member
Jun 3, 2025
15
I am so so sorry you're suffering. I have been on and off several anti depressants over the years to help with chronic pain. I was on Effexor a very brief period of time, but upon discontinuing I developed PGAD..pretty much the opposite of what you have. Torture. For over a year it was absolutely maddening.. I wanted to jump out of my skin every single moment of the day. It eventually lessened quite a bit and I have no idea how or why as I know a lot of people aren't so "lucky." I now have other health issues that have destroyed my life, so I completely empathize with you.
I'm hoping you find relief both mentally and physically❤️‍🩹
 
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Paizen

Paizen

Student
Feb 5, 2025
106
I am sorry to suffer as well. The past 4 years have been a nightmare and this past year is like living a daily hell. I cannot describe how awful this is, to wake up one day unable to feel love for your own family. To see your mother as a stranger and no longer feel love for them is a pain I wouldn't wish on anyone. It has taken everything in me to still be alive.

I am sorry, it is a tragedy. How long have you had PSSD for if you don't mind me asking? And I am not familiar with ctb. What is that?

She said she often contemplated suicide and it took years for her to eventually develop a relationship emotionally and build a successful life of research into the condition and spread awareness of PSSD. She told me to try and look for moments I don't notice the PSSD to look for support from family and friends for help. I have been in a support group for PSSD for several months now but I still struggle to keep living. We all share how we feel regularly and check in with each other but living life without emotions or sexual feelings and numb genitals will be very hard to keep going with. I have considered meeting with therapists that are aware of PSSD but it has been hard to find any. I don't wanna sound negative but this is the reality for me but I loved my life before all this happened. Thank you for responding I appreciate your advice.
I didn't even need SSRIs to feel no love. It just kind of happened naturally.
 
ketopia

ketopia

Missing my Mom
Jun 4, 2025
84
I'm so sorry. I'm borderline ace myself but lexapro turned me into a total zombie. It didn't do anything to get rid of the depression or SI, it just took away every other emotion. So it turned me into the most stable and focused suicidal person that ever lived. I attempted without a single ounce of fear, sadness, guilt, or anything. I was just operating like a machine.

Now I'm going to attempt again but I feel horrible about it. Honestly I don't know what's better
 
A

Alreadylate

Member
Jun 8, 2025
34
About four years ago, I started taking Lexapro (20mg). Within a few months, I felt extremely suicidal, depressed, and anxious. I had never been suicidal before taking an SSRI—I only had mild anxiety, but my doctor insisted this medication would help. When I told him it was making me suicidal, he added Effexor at the highest dose.

This combination caused genital numbness and made me so suicidal that I began researching assisted suicide. I begged my doctor to let me stop, but he told me to keep taking it. I quit cold turkey, and thankfully, the numbness went away, and I stabilized. But the suicidal thoughts lingered.

A year later, I tried Zoloft. The same thing happened—this time with memory problems, depersonalization, and such severe panic attacks that I couldn't even drink coffee. I stayed on it for another year before quitting last January. At first, I felt better—my anxiety was still there, but the suicidal thoughts faded.

Then, after a family crisis and a sleepless night, I started getting brain shocks. For three months, I barely slept, and my anxiety became so extreme that my hair fell out. A doctor prescribed an antipsychotic, which made me lose even more hair (all over my body) and turned me into a zombie. I quit after two weeks.

Hospitalized and desperate, I was forced onto a mood stabilizer and Zoloft again. The suicidal thoughts returned. My parents made me try Cymbalta, which left me sleepless for five days, completely numb genitally, and with such bad brain fog and memory issues that I'd go to fill up my car and pay for gas, then drive away without filling up. My brain burned constantly, like it was on fire. I quit cold turkey again.

Now, a year later, I'm a shell of myself. I feel no emotions—no joy from music, no love for my family (though I know I love them), no runner's high. I used to be passionate and full of life; now, I'm empty. I am starting to lose hope that I can continue to live life like this. I should also add that I have been on no medication for over a year now. I still to this day have numb genitals and a lack of orgasms. I cannot feel joy or sadness in any form. Cymbalta took my soul and sense of self and my pleasure.
Psychiatry is horrendous... They don't stop doing this to everybody. Everytime I took antidepressants automatically became extremely suicidal, and taking any kind of pills in general make your symptoms worse eventually or even new symptos arise. I think antidepressants or anxiety pills, antipsycotics whatever, they all make you loss your sex drive or significantly reduce it, what for me is the most depressing thing. Also, antidepressants are not recommended for suicidal people, why they keep giving them to suicidal people? I think medicine is a circus specially when it comes to mental health...In 50's they used to do lobotomies now they do this. They are not interested in you to recover, they just want money. Stop taking medicines.
 
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G

gameoverman

Member
May 25, 2025
17
My life has been completely ruined by PSSD too. I wonder why this curse happened to me especially considering it's a rare condition. What did I do to deserve this. Having PSSD is a fate worse than death. My PSSD is different than typical though: on top of anhedonia,genital numnbness and emotional blunting I also have debilitating anxiety. It's pure torture "living" with this.
 
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kaleisgreatinsalad

Member
Mar 17, 2025
10
My life has been completely ruined by PSSD too. I wonder why this curse happened to me especially considering it's a rare condition. What did I do to deserve this. Having PSSD is a fate worse than death. My PSSD is different than typical though: on top of anhedonia,genital numnbness and emotional blunting I also have debilitating anxiety. It's pure torture "living" with this.
I agree, I am sorry we have to suffer my friend. I hope one day we will be free of this condition
 

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