Metoclopramide vs Zofran (anti-e)

[Mistress Death]

Which is better for use with N? I believe I will have access to both.

 

[Ntothed]

Which is better for use with N?

I bought Meto because everyone on here said it was the best choice and it was easy to obtain. I bought from a Greek seller and it was in the US within one week. Not sure which is theoretically better though.

 

[Mistress Death]

I bought Meto because everyone on here said it was the best choice and it was easy to obtain. I bought from a Greek seller and it was in the US within one week. Not sure which is theoretically better though.

I just edited it, but I think I'll have access to both or at least I'll be able to get either one.

 

[JohnDoe1]

Use both if you can...both work on different receptors in the brain...together, they would provide additional protection against nausea...

 

[JohnDoe1]

60 mg Meto and 16 mg Zofran

 

[Mistress Death]

60 mg Meto and 16 mg Zofran

Why both and why those dosages? Does't the dosage matter with my weight? I am just under 68kg.

 

[JohnDoe1]

Why both and why those dosages? Does't the dosage matter with my weight? I am just under 68kg.

Receptors that control vomiting in the brain include:

- acetylcholine
- dopamine
- H-1 receptor
- NK-1 receptor
- 5-HT3 receptor

Meto binds to the dopamine recptor...and Zofran binds to the 5-HT3 receptor...

So, both provide additive benefit for reducing nausea and vomiting.

The dosages I mentioned are the ones that are recommended by different authors..I have taken as much as 60 mg meto and 40 mg zofran...with no ill effects...

weight-based dosing is not relevant in case of anti-emetics.

 

[JohnDoe1]

But, if you have to choose only one...then Meto is the better choice...it speeds up gastric emptying...and is a weak 5-HT3 receptor agonist also...

 

[Deleted member 4993]

Regimen
Wiki author best option 45 min prior to drug ingestion, take 40 mg Metoclopramide and 8-16 mg Ondansetron
Wiki author second best option 45 min prior to drug ingestion, take 40 mg Domperidone and 8-16 mg Ondansetron
Dr Nitschke's advice 40 min prior to drug ingestion, take 60 mg Metoclopramide
Dignitas' procedure as per their webpage 30 min prior to drug ingestion, take 20-30 mg liquid Metoclopramide
Death with Dignity George Eighmey's advice 60 min prior to drug ingestion, take 20-40 mg Metoclopramide and 8-16 mg Ondansetron

 

[Made4TV]

I take both for a condition called gastroparesis. Johndoe1 is right... they differ but combined are golden.

 

[ddutch]

https://en.m.wikibooks.org/wiki/Suicide/Toxification/Antiemetic_regimen

Here you can find the regime for taking N

It is in the section anti emetics option

 

[how2toGetout]

Which is better for use with N? I believe I will have access to both.

How do you get Meto or Zofran? I don't have access to them thru prescription. Is there a way to buy them in US without prescription (thru online websites from US or other countries)? I want to use Meto or Zofran for SN (Sodium Nitrite).