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plzoffme

plzoffme

Member
Jun 30, 2025
63
Hey everyone :)

So I have been getting a lot of messages about my method to CTB, which is to use Isotonitazene. I wanted to make this thread to explain what it is and how it works.
I want to give back to this forum is some way before I CTB. I hope someone can make use of this info to leave peacefully :)

Video about this substance:

What is it?
Isotonitazene is a synthetic opioid first synthesized in the 1950s as an attempt to develop safer, more potent opioid analgesics,
but it was never approved for medical use anywhere in the world. It belongs to the 2-benzylbenzimidazole class of compounds,
which are structurally distinct from fentanyl analogues, and acts as a potent full mu-opioid receptor agonist, making it highly effective
at producing analgesia and euphoria. It is estimated to be 1000 times more potent than morphine and approximately 3.7 to 1500 times more potent than fentanyl.


How it works?
Isotonitazene is a synthetic opioid that functions as a full agent at the μ-opioid receptor (MOR), meaning it binds to and activates these receptors throughout the brain and body, producing effects such as euphoria, relaxation, pain relief, and slowed breathing. It severely depressing the central nervous system, primarily by slowing and eventually stopping breathing.


Why is this a good CTB method?
First, this substance is 2-3 times if not more potent then Fentanyl. Once taken you will go unconscious almost immediately when ingested.
There is no pain, no need to worry about swallowing anything, unless taken orally. You do not need to worry about throwing up or mixing anything.
Also, one of the major reasons this is such a good CTB method is because the drug
Naloxone, which is used to stop Fentanyl overdoses is not strong enough
for Isotonitazene, You need ALOT to come back. You only need a VERY VERY small amount to OD on. 2-5 MGs will do the job. Most high tolerance users

only use 20-30 UGs NOT even MGs.


Where to buy it?

Currently, I have only found it through Dark web markets. Its cost around $100 per gram which is WAY MORE then enough :)
You need Tor browser to access the website. I can't list the full source here as it would break the sites guidelines but PM me for info.


Final thoughts :)
Like SN, this slows down breathing till you die from the lack of oxygen your brain gets and go unconscious. I believe this method is better then SN for the following reasons.
1. You do not have to worry about mixing anything.
2. You do not have to worry about a salty taste in your mouth or if you will throw it up.
3. It is pretty much an instant death for someone with 0 tolerance to synthetic opiates.
4. Super cheap and easy to source.
 
Last edited:
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G

gameoverman

Member
May 25, 2025
31
Hey everyone :)

So I have been getting a lot of messages about my method to CTB, which is to use Isotonitazene. I wanted to make this thread to explain what it is and how it works.
I want to give back to this forum is some way before I CTB. I hope someone can make use of this info to leave peacefully :)

What is it?
Isotonitazene is a synthetic opioid first synthesized in the 1950s as an attempt to develop safer, more potent opioid analgesics,
but it was never approved for medical use anywhere in the world. It belongs to the 2-benzylbenzimidazole class of compounds,
which are structurally distinct from fentanyl analogues, and acts as a potent full mu-opioid receptor agonist, making it highly effective
at producing analgesia and euphoria. It is estimated to be 1000 times more potent than morphine and approximately 3.7 to 1500 times more potent than fentanyl.


How it works?
Isotonitazene is a synthetic opioid that functions as a full agent at the μ-opioid receptor (MOR), meaning it binds to and activates these receptors throughout the brain and body, producing effects such as euphoria, relaxation, pain relief, and slowed breathing. It severely depressing the central nervous system, primarily by slowing and eventually stopping breathing.


Why is this a good CTB method?
First, this substance is 2-3 times if not more potent then Fentanyl. Once taken you will go unconscious almost immediately when ingested.
There is no pain, no need to worry about swallowing anything, unless taken orally. You do not need to worry about throwing up or mixing anything.
Also, one of the major reasons this is such a good CTB method is because the drug
Naloxone, which is used to stop Fentanyl overdoses is not strong enough
for Isotonitazene, You need ALOT to come back. You only need a VERY VERY small amount to OD on. 2-5 MGs will do the job. Most high tolerance users

only use 20-30 UGs NOT even MGs.


Where to buy it?

Currently, I have only found it through Dark web markets. Its cost around $100 per gram which is WAY MORE then enough :)
You need Tor browser to access the website. I can't list the full source here as it would break the sites guidelines but PM me for info.


Final thoughts :)
Like SN, this slows down breathing till you die from the lack of oxygen your brain gets and go unconscious. I believe this method is better then SN for the following reasons.
1. You do not have to worry about mixing anything.
2. You do not have to worry about a salty taste in your mouth or if you will throw it up.
3. It is pretty much an instant death for someone with 0 tolerance to synthetic opiates.
4. Super cheap and easy to source.
Hey, this is a very good looking method to CTB. Could you please PM and give me some info on how to get Isotonitazene from dark web?
 
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G

gameoverman

Member
May 25, 2025
31
I messaged you friend with info :)
I got notification that you started a private conversation with me but somehow I can't access it.
I don't know why,maybe I don't have enough posts on the forum so I don't have the ability to PM or I'm just stupid. Any ideas?
 
L

lasttogo

Waiting for.... Something
Aug 20, 2025
69
I got notification that you started a private conversation with me but somehow I can't access it.
I don't know why,maybe I don't have enough posts on the forum so I don't have the ability to PM or I'm just stupid. Any ideas?
My messages didn't start working until I had a higher amount of posts, not super sure however
Hey everyone :)

So I have been getting a lot of messages about my method to CTB, which is to use Isotonitazene. I wanted to make this thread to explain what it is and how it works.
I want to give back to this forum is some way before I CTB. I hope someone can make use of this info to leave peacefully :)

What is it?
Isotonitazene is a synthetic opioid first synthesized in the 1950s as an attempt to develop safer, more potent opioid analgesics,
but it was never approved for medical use anywhere in the world. It belongs to the 2-benzylbenzimidazole class of compounds,
which are structurally distinct from fentanyl analogues, and acts as a potent full mu-opioid receptor agonist, making it highly effective
at producing analgesia and euphoria. It is estimated to be 1000 times more potent than morphine and approximately 3.7 to 1500 times more potent than fentanyl.


How it works?
Isotonitazene is a synthetic opioid that functions as a full agent at the μ-opioid receptor (MOR), meaning it binds to and activates these receptors throughout the brain and body, producing effects such as euphoria, relaxation, pain relief, and slowed breathing. It severely depressing the central nervous system, primarily by slowing and eventually stopping breathing.


Why is this a good CTB method?
First, this substance is 2-3 times if not more potent then Fentanyl. Once taken you will go unconscious almost immediately when ingested.
There is no pain, no need to worry about swallowing anything, unless taken orally. You do not need to worry about throwing up or mixing anything.
Also, one of the major reasons this is such a good CTB method is because the drug
Naloxone, which is used to stop Fentanyl overdoses is not strong enough
for Isotonitazene, You need ALOT to come back. You only need a VERY VERY small amount to OD on. 2-5 MGs will do the job. Most high tolerance users

only use 20-30 UGs NOT even MGs.


Where to buy it?

Currently, I have only found it through Dark web markets. Its cost around $100 per gram which is WAY MORE then enough :)
You need Tor browser to access the website. I can't list the full source here as it would break the sites guidelines but PM me for info.


Final thoughts :)
Like SN, this slows down breathing till you die from the lack of oxygen your brain gets and go unconscious. I believe this method is better then SN for the following reasons.
1. You do not have to worry about mixing anything.
2. You do not have to worry about a salty taste in your mouth or if you will throw it up.
3. It is pretty much an instant death for someone with 0 tolerance to synthetic opiates.
4. Super cheap and easy to source.
This really makes me wonder if the drug combo I have currently would do it for me because they affect me awfully, I think one of them almost killed me this morning. However it was incredibly terrifying, might even go as far as saying traumatizing because I did it by accident. The cns depressing part is the part that seems to be really effective in these ctb methods.
 
Last edited:
G

gameoverman

Member
May 25, 2025
31
You have to inject this substance into your vein or can it be taken orally?
 
C

copioushopelessness

Member
Aug 27, 2025
55
I messaged you friend with info :)
Tried to msg you, not sure if it went through. Also I'm wondering, do I need a certain amount of interactions before I can post? I can't seem to figure out how to post.
 
Malfunction

Malfunction

Student
Jul 27, 2024
139
Sounds interesting.

Not sure if I'd do it or not. Things like Tylenol 3 or Tramacet affect my breathing (asthma, sleep apnea). And those are mild. I'm already on edge with taking pain killers.

If it actually knocked me out quickly before the breathing issue kicked in then I might be tempted.

Thanks for bringing this forward, Its appreciated.
 
F

final.call

Member
Aug 16, 2024
6
Hey everyone :)

So I have been getting a lot of messages about my method to CTB, which is to use Isotonitazene. I wanted to make this thread to explain what it is and how it works.
I want to give back to this forum is some way before I CTB. I hope someone can make use of this info to leave peacefully :)

Video about this substance:

What is it?
Isotonitazene is a synthetic opioid first synthesized in the 1950s as an attempt to develop safer, more potent opioid analgesics,
but it was never approved for medical use anywhere in the world. It belongs to the 2-benzylbenzimidazole class of compounds,
which are structurally distinct from fentanyl analogues, and acts as a potent full mu-opioid receptor agonist, making it highly effective
at producing analgesia and euphoria. It is estimated to be 1000 times more potent than morphine and approximately 3.7 to 1500 times more potent than fentanyl.


How it works?
Isotonitazene is a synthetic opioid that functions as a full agent at the μ-opioid receptor (MOR), meaning it binds to and activates these receptors throughout the brain and body, producing effects such as euphoria, relaxation, pain relief, and slowed breathing. It severely depressing the central nervous system, primarily by slowing and eventually stopping breathing.


Why is this a good CTB method?
First, this substance is 2-3 times if not more potent then Fentanyl. Once taken you will go unconscious almost immediately when ingested.
There is no pain, no need to worry about swallowing anything, unless taken orally. You do not need to worry about throwing up or mixing anything.
Also, one of the major reasons this is such a good CTB method is because the drug
Naloxone, which is used to stop Fentanyl overdoses is not strong enough
for Isotonitazene, You need ALOT to come back. You only need a VERY VERY small amount to OD on. 2-5 MGs will do the job. Most high tolerance users

only use 20-30 UGs NOT even MGs.


Where to buy it?

Currently, I have only found it through Dark web markets. Its cost around $100 per gram which is WAY MORE then enough :)
You need Tor browser to access the website. I can't list the full source here as it would break the sites guidelines but PM me for info.


Final thoughts :)
Like SN, this slows down breathing till you die from the lack of oxygen your brain gets and go unconscious. I believe this method is better then SN for the following reasons.
1. You do not have to worry about mixing anything.
2. You do not have to worry about a salty taste in your mouth or if you will throw it up.
3. It is pretty much an instant death for someone with 0 tolerance to synthetic opiates.
4. Super cheap and easy to source.

This is very interesting, may I know how you came to discover Isotonitazene as a method to CTB?

Most of us will probably not have heard of this substance before so I guess more research and testing is needed before we can deem it as safe and effective of a method as SN.

I would like to PM you, however unfortunately I can't because I don't have permission to do so yet.
 
Wrath

Wrath

Long live my dead dreams.
Dec 12, 2024
36
EDIT:: I withdraw my opinion, I was being stupid and belittling. Sorry. Just be careful if you're thinking of buying something on schedule 1.
 
Last edited:

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