Frustrated

[sky7]

So I am back after a rather log hiatus. I want to ctb but the only thing at my disposal are about a month's supply of risperdone and abilify. Somewhere I read that antipsychotics can be lethal at 6 times the therapeutic range but then I read that both of these are safe in overdose. Which is frustrating. I have tried od'ing on the abilify before with a grand result of some nausea and dry heaving. Not pleasant and most definitely not effective. I read all these stories of people who successfully od and I want to know on what and how'd they get it. I I personally know someone who successfully od'd on psych meds though I don't know what kind.

 

[MotherOfCats]

So I am back after a rather log hiatus. I want to ctb but the only thing at my disposal are about a month's supply of risperdone and abilify. Somewhere I read that antipsychotics can be lethal at 6 times the therapeutic range but then I read that both of these are safe in overdose. Which is frustrating. I have tried od'ing on the abilify before with a grand result of some nausea and dry heaving. Not pleasant and most definitely not effective. I read all these stories of people who successfully od and I want to know on what and how'd they get it. I I personally know someone who successfully od'd on psych meds though I don't know what kind.

I very nearly succeeded on clomipramine, as my psych made the mistake of asking me if I was suicidal when she put me on it as it's dangerous in OD. I was found too early and spent a week in ICU. It's an atypical antidepressant and isnt prescribed very often.

 

[faust]

"This study is based on 239 cases of aripiprazole exposure with data from the DPIC, patient medical records and Danish National Hospital Registry. We found that ingestion of aripiprazole in overdose was generally well tolerated and caused no short‐term fatalities. The most prevalent symptom was light somnolence. This is in line with previously reported cases and studies 11-17. A possible explanation for this could be the antagonistic effect of aripiprazole on the histamine H1 receptor. Aripiprazole has moderate affinity for the receptor (Ki value of 61 nM) and limited sedating effect with therapeutic doses, but accentuation of this receptor interaction may explain the sedation seen in overdoses. Our study revealed no severe cardiotoxicity in the single‐drug exposure group, which is consistent with previous studies concerning overdose with aripiprazole 3. Polcwiartek et al. found that aripiprazole had a safe cardiac profile 18, and an updated search of the literature revealed no reports of severe cardiotoxicity.
..............................
As mentioned, none of the reported cases were lethal. Nevertheless, we found a significantly increased long‐term mortality among the reported cases when compared to an age‐ and gender‐matched background population. The reason for the increased mortality is most likely due to an increased occurrence of psychiatric illness, suicide and abuse among the cases. This is in agreement with previous studies which have also demonstrated an increased risk of subsequent suicide after admission to a hospital with a diagnosis of drug poisoning "

Source: https://onlinelibrary.wiley.com/doi/full/10.1111/bcpt.12902

Conclusion: it is nearly impossible to die this way.
Opinion: the only reliable method when antidepressants or antipsychotics are used as primary substances is Amitriptyline cocktail. Other medication is a gamble.