Advice request for sleeping pills

[Starbugz]

Can anyone advise if a Doxylamine Succinate is a possible sleeping pill overdose? I understand it depends on the individual and body weight but any steer ref volumes would be appreciated

 

[sleepy dog]

Can anyone advise if a Doxylamine Succinate is a possible sleeping pill overdose? I understand it depends on the individual and body weight but any steer ref volumes would be appreciated

From Wikipedia:

TOXICITY

Doxylamine succinate is generally safe for administration to healthy adults. The median lethal dose (LD50) is estimated to be 50–500 mg/kg in humans. Symptoms of overdose may include dry mouth, dilated pupils, insomnia, night terrors, euphoria, hallucinations, seizures, rhabdomyolysis, and death. Fatalities have been reported from doxylamine overdose. These have been characterized by coma, tonic-clonic (or grand mal) seizures and cardiorespiratory arrest. Children appear to be at a high risk for cardiorespiratory arrest. A toxic dose for children of more than 1.8 mg/kg has been reported. A 3-year-old child died 18 hours after ingesting 1,000 mg doxylamine succinate. Rarely, an overdose results in rhabdomyolysis and acute renal failure.

Studies of doxylamine's carcinogenicity in mice and rats have produced positive results for both liver and thyroid cancer, especially in the mouse. The carcinogenicity of the drug in humans is not well studied, and the IARC lists the drug as "not classifiable as to its carcinogenicity to humans"